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PhD Scholarship in Rational Evolution of Enzymes 2010, DTU, Denmar

Published on Dec 29 2010 // PhD, Scholarships in Denmark, Western Europe

We are looking for talented candidates for an international-level PhD degree in Rational Evolution of Enzymes at The Technical University of Denmark (DTU), DTU Chemistry, funded by the Danish National Research Council for Technology and Production. Approximate starting date April 1 2011.

This new, international research project involves the study of the copper-containing enzymes known as laccases: Why did they evolve to their particular current structures, and how are these structures evolutionary optimized for stability and function under extreme environmental conditions, in particular high temperature?

The theoretical knowledge gained in the early part of the project will be used to rationally guide the evolution of new breeds of superstable laccases in the lab. The research area of computational protein evolution is of growing importance, because of the need to process increasingly complex information in the search for new industrial enzymes, both within academic research and within the private sector.

  • Qualifications

Candidates should have a master’s degree in engineering or science or a similar degree with an academic level equivalent to the master’s degree. Both theoretical and experimental skills need to be proven. Relevant theoretical skills: Computational biology/chemistry, mathematical modeling, biophysics, quantum chemistry, computers/programming. Relevant experimental skills: General Lab experience, protein chemistry, protein expression, mutagenesis, and/or screening.

  • Approval and Enrolment

The scholarships for the PhD degree are subject to academic approval, and the candidates will be enrolled in one of the general degree programmes of DTU. For information about the general requirements for enrolment and the general planning of the scholarship studies, please see theDTU PhD Guide.

  • Salary and appointment terms

The salary and appointment terms are consistent with the current rules for PhD degree students. The period of employment is 3 years.

  • Further information

Further information may be obtained from Dr. Kasper P. Kepp, e-mail:

You can read more about our research on

Do NOT send applications to this e-mail address, but use the electronic submission system – see below!

  • Application

We must have your online application by 15 February 2011. Please open the link “apply for this job online”, fill in the application form and attach the following documents;

  • A letter motivating the application (cover letter)
  • Curriculum vitae
  • Grade transcripts and BSc/MSc diploma
  • Conversion of grade averages to Danish grades (see guidelines and excel spreadsheet for the conversion here).

Candidates may apply prior to obtaining their master’s degree, but cannot begin before having received it.

All interested candidates irrespective of age, gender, race, handicap, religion or ethnic background are encouraged to apply.


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